The acronym RAPID is a simple way to remember the correct steps for preparing and administering MIGRANAL:
A step-by-step video demonstration of the preparation and administration of MIGRANAL.
A quick guide to the simple steps for preparing and administering MIGRANAL.
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Migranal® (dihydroergotamine mesylate, USP) Nasal Spray is indicated for the acute treatment of migraine headaches with or without aura. Migranal Nasal Spray is not intended for the prophylactic therapy of migraine or for the management of hemiplegic or basilar migraine.
Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of DIHYDROERGOTAMINE with potent CYP3A4 inhibitors including protease inhibitors and macrolide antibiotics. Because CYP3A4 inhibition elevates the serum levels of DIHYDROERGOTAMINE, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. Hence, concomitant use of these medications is contraindicated.
Please click here for full Prescribing Information for MIGRANAL Nasal Spray, including Boxed Warning and Patient Information.