The American Headache Society classifies MIGRANAL Nasal Spray as effective Level A treatment for acute migraines.1*
The unique nasal spray is appropriate for different patient types, including the following scenarios:
MIGRANAL can be used for patients who wake up with moderate to severe migraine.2-4
MIGRANAL works differently than commonly prescribed migraine medicine.2-4,9,12
MIGRANAL is believed to have a low likelihood of causing MOH.14,15
The active ingredient in MIGRANAL may target early- and late-phase migraine pain.2-4,15
MIGRANAL is directly absorbed through the nasal mucosa, avoiding gastric stasis and delayed gastrointestinal absorption.4
*Level A: Medications are established as effective for acute migraine treatment based on available evidence.1
*Based on results from the American Migraine Prevalence and Prevention (AMPP) study.
OTC, over the counter.
*Nausea half of the time or more.
MIGRANAL® (dihydroergotamine mesylate) Nasal Spray is indicated for the acute treatment of migraine headaches with or without aura. MIGRANAL Nasal Spray is not intended for the prophylactic therapy of migraine or for the management of hemiplegic or basilar migraine.
Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of DIHYDROERGOTAMINE with potent CYP3A4 inhibitors including protease inhibitors and macrolide antibiotics. Because CYP3A4 inhibition elevates the serum levels of DIHYDROERGOTAMINE, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. Hence, concomitant use of these medications is contraindicated.
Please click here for full Prescribing Information for MIGRANAL Nasal Spray, including Boxed Warning and Patient Information.